There would be hardly any adult that hasn’t experienced moments of feeling low and unexpected mood swings. The conditions improve as the environmental factors that triggered the condition change or as the mind gains strength to process the negative feelings and recover. However, this does not happen with everyone and for them, the mood does not improve at a normal pace.
Consistent feeling of unhappiness that affects daily functioning negatively could indicate that you might be suffering from the mental condition, depression. The combination of suitable lifestyle changes and proper medication can help overcome depression and hemp CBD is being suggested as a potent medication that could improve the symptoms of depression.
Role Of Neural Degeneration In Depression
Most popular explanation for depression is serotonin deficiency and there is no denying that the chemical plays a role in regulating the mood. However, depression cannot be explained merely by pointing out the levels of serotonin in the body but structural changes in the brain that occur because of trauma or chronic stress could primarily lead to a depression state.
In people with depression, the hippocampus, which is a brain region responsible for regulating emotions, learning and memory, could undergo some alterations and even shrink and the process is referred to as brain degeneration. The hippocampus is capable of recovering by growing new neurons and forming new neural connections by a process referred to as neural regeneration.
Antidepressants work by stimulating neural regeneration in the hippocampus, which explains why it takes some time for their effects to kick in.
CBD Stimulating Neural Regeneration
The only CBD drug approved by FDA is Epidolex that is used to treat seizure symptoms in epileptic people and studies have suggested that CBD succeeds in reducing seizure frequency by protecting the neurons in the hippocampus. Hippocampus is the brain area that is atrophied in people with depression and the fact sheds light on the potential of CBD in treating depression.
Studies on rats have suggested that CBD usage increased the levels of the chemical anandamide in the hippocampus and its elevated levels could promote neuron growth. Brain derived neurotrophic factor(BDNF) is a protein that ensures the survival of existing neurons and promotes the growth of new neurons and synapses. Multiple studies on rodents have suggested that CBD use increases the level of BDNF in the hippocampus and reduces depression symptoms.
CBD is a safer anti-depressant alternative when compared with many other medications that have multiple side effects.