The world has seemingly fallen head over heels in love with this fabulous herbal extract. The fan following that throng this herbal extract is majorly based in the United States and the United Kingdom- a recent statistic says that close to 10% of the population has tried their hands on the herbal medication. The growth that we can anticipate in the coming years is truly mind-boggling, to say the least. It is expected that the industry will turn into a $5 billion powerhouse in the pharmaceutical space within the year 2025.
However, unlike what most people believe, it isn’t only the CBD in the CBD bottle that contributes to the range of health benefits that user’s experience. The CBD bottle consists of hundreds of similar substances called cannabinoids. And along with that misconception, people also believe that the raw hemp plant from which CBD is extracted is teeming with the magic elixir. But, that is not the case.
Within the inner circle of cannabinoid research and science, this particular precursor has not got the limelight and the recognition that it’s transformed self, namely CBD has gotten. For the most part, its reputation is shunned.
This false notion or lack thereof is starting to wane away for good. The research into the raw form of CBD was still in the shadow and for a good part non-existent- This has changed in recent years. To help in aiding the rise, there is increased media attention that has done nothing but propels this precursor even higher.
Who are we talking about?
The Precursor to CBD
It is none other than Cannabidiolic acid (CBDA), which is the botanical precursor to CBD.
What is CBDA and what more should you know as a consumer?
It is found in raw hemp and is the acid form of CBD. When CBDA is exposed to sunlight or heat, it undergoes decomposition and breaks down to form CBD. This process is called Decarboxylation. It involves the removal of the Carboxyl group.
The process of decarboxylation occurs not only in cannabis and its derivatives but even in our very own body- cellular respiration is a form of decarboxylation, wherein CO2 is exhaled as a by-product of the metabolism.
It is often that, decarboxylated cannabinoids were regarded as the activated forms of the dormant precursors, and was regarded as the ones that impart the most therapeutic effects in users. However, the therapeutic effects of CBD were graced by a revelation after studies showed that CBDA activation of 5-HT1A serotonin receptors is significantly more potent in the effects of binding than CBD. CBDA has a stronger affinity towards a particular antagonist called as GPR55- A receptor that is believed to cause cancer and lower bone density that could lead to early osteoporosis. The binding effectively lowers its efficiency.
CBDA could be the link that is helping in reducing the onset of cancer, epilepsy, treatment-resistant nausea, vomiting and anxiety.
CBDA For Vomiting
Serotonin is one of the more widely known neurotransmitters and for good reason- it plays a big role in mood regulation. But rather than making your feel all giddy and happy, the reach of this particular neurotransmitter goes further beyond that. Serotonin helps in diverse physiological functions like intestinal movement and vomiting.
Much of this is because of the interaction that CBDA has with the 5-HT1A serotonin receptor. The firmer and stronger binding of CBDA with the said receptor than CBD helps in suppressing the feeling of vomiting and motion sickness that is caused by toxins.
What is even more exciting is how CBDA allows in suppressing the feeling of anticipatory nausea, such as that which one experiences prior to chemotherapy when the patient feels horrible even before the treatment has officially begun.
To add to the icing is the non-intoxicating nature of CBDA. Recent research showed that a low dosage of CBDA enhanced the pharmaceutical drug’s anti-nausea effects. You can seek treatment without the barrage of long-term side effects that come in the fine print of most over-the-counter prescription drugs.
Battling Epilepsy With CBDA
CBDA can potentially be the next big thing when it comes to natural anti-epileptic medication. The benefits list of CBDA includes effective seizure reduction. Further research needs to be conducted to figure out how we can best use it. But nevertheless, the future looks bright in this regard. The anti-epileptic properties of CBD and CBDA along with the several other cannabinoids can help breathe a new life into patients who are finding themselves stopped in their tracks.
The Final Note
Adding some CBDA into your life can have a profound effect on turning it for the better. Some of the CBD products available are those that are still not decarboxylated- Do give these a try. There are several things that are yet to be uncovered regarding this still enigmatic cannabinoid. It is only a matter of time until that is done, and until then we are hopeful.